The Reproducibility of Lists of Differentially Expressed Genes in Microarray Studies
نویسندگان
چکیده
منابع مشابه
The Reproducibility of Lists of Differentially Expressed Genes in Microarray Studies
Reproducibility is a fundamental requirement in scientific experiments and clinical contexts. Recent publications raise concerns about the reliability of microarray technology because of the apparent lack of agreement between lists of differentially expressed genes (DEGs). In this study we demonstrate that (1) such discordance may stem from ranking and selecting DEGs solely by statistical signi...
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High throughput technologies, such as gene expression arrays and protein mass spectrometry, allow one to simultaneously evaluate thousands of potential biomarkers that could distinguish different tissue types. Of particular interest here is distinguishing between cancerous and normal organ tissues. We consider statistical methods to rank genes (or proteins) in regards to differential expression...
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رشد انفجاری تکنولوژی فرصت های آموزشی مهیج و جدیدی را پیش روی فراگیران و آموزش دهندگان گذاشته است. امروزه معلمان برای اینکه در امر آموزش زبان بروز باشند باید روش هایی را اتخاذ نمایند که درآن ها از تکنولوژی جهت کمک در یادگیری زبان دوم و چندم استفاده شده باشد. با در نظر گرفتن تحولاتی که رشته ی آموزش زبان در حال رخ دادن است هم اکنون زمان مناسبی برای ارزشیابی نگرش های موجود نسبت به تکنولوژی های جدید...
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چکیده ندارد.
15 صفحه اولRaking and Selection of Differentially Expressed Genes from Microarray Data
This paper presents adaptive algorithms for ranking and selecting differentially expressed genes from microarray data. A ranking method originally proposed in [1] is adapted and supplemented with Hausdorff distancebased ranking method to improve the performance of the ranking algorithm. A weighted fusion scheme is developed to fuse the ‘mean’ and the Hausdorff distance-based ranking methods to ...
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ژورنال
عنوان ژورنال: Nature Precedings
سال: 2007
ISSN: 1756-0357
DOI: 10.1038/npre.2007.306.2